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Cell - Life Science Journal am 16.03.2021 23:00:00

Structure and gating mechanism of the α7 nicotinic acetylcholine receptor

Zusammenfassung: ... Cryo-EM structures of the α7 nicotinic acetylcholine receptor in three major conformational states of the gating cycle—resting, activated, and desensitized—along with functional studies reveal components involved in calcium conductance and allosteric coupling of ligand binding to channel opening. ...

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